From a promising alternative for the flu shot to hope for a “universal” vaccine, we take a look at how scientists at Johnson & Johnson are exploring novel ideas for preventing and treating the flu.

When it struck, the 1918 flu pandemic—one of the deadliest outbreaks on record—killed up to 50 million. As flu season begins, we look at how far we’ve come in fighting the viral infection, including promising work being done on a universal vaccine.

Is it too late to get one this year? Is there anyone who shouldn’t get it? We answer these and other pressing questions about the vaccine so you can stay healthy this flu season.