- UK
- Our innovation
- Focus areas
- Pulmonary Hypertension
Pulmonary Hypertension
Our focus in pulmonary hypertension
We are spearheading a new era for those living with PAH to transform the disease into a long-term manageable condition, so that patients can live fulfilling lives.
What is PAH?
In the UK, approximately 55 people per million—nearly 4,000 individuals—are affected by PAH. 1, 2
The risk of developing PAH increases with age and is particularly relevant for those living with conditions such as Scleroderma, Congenital Heart Disease, or other Connective Tissue Disorders (CTD). 1 Our focus is therefore on supporting people in these groups with diagnosis and managing the condition.
With PAH, symptoms might not appear until the condition is advanced, meaning the condition can be difficult to diagnose. 1
We understand how PAH impairs daily life
We have demonstrated our UK commitment to PAH over the past five years through:
Our Vision in PAH
At J&J, our vision in PAH is centered on reducing diagnosis time by supporting education and screening to accelerate referrals to specialists. We are committed to improving the health and quality of life of those affected by PAH, including patients, carers, and families. Through partnerships with the NHS, we aim to empower healthcare professionals and enhance PAH management across the UK healthcare system, while maximising the clinical benefits of our treatments for better patient outcomes. We are driving research and innovation to discover new ways to tackle PAH, and together with patients, healthcare professionals, and advocates, we are making meaningful progress to improve lives and advance PAH care.
PAH Podcasts
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We are committed to ensuring that people living with PAH in the UK are diagnosed early, supported holistically, and able to access the care they need. Our work has brought unique perspectives, opportunities and capabilities that continue to support the PAH community.
Our heritage in PAH
In June 2017, Actelion Pharmaceuticals Ltd became part of the Janssen Pharmaceutical Companies of Johnson & Johnson. Supported by Actelion’s 20-year heritage of pioneering innovation in PAH, we are working to reach more patients and aim to help tackle the diagnosis gap that can delay access to the care that patients need.
We bring to the field of PAH a remarkable track record in scientific discovery and a deep patient-centric focus.
Partner with us
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1: Humbert M et al, (2022), 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension; European Heart Journal; 00, 1–114.
2: Office for National Statistics. UK population. Available at:
https://www.ons.gov.uk/
3: Armstrong I, et al. The patient experience of pulmonary hypertension: a large cross sectional study of UK patients. BMC Pulm Med 2019; 19:67.
CP-486604 | October 2025