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      DePuy Synthes Companies Introduces Zero-Profile Plate with Allograft Spacer for Neck Surgery

      DePuy Synthes Companies Introduces Zero-Profile Plate with Allograft Spacer for Neck Surgery

      ZERO-P NATURAL™ Plate Coupled with the CC Natural Allograft Spacer Offers Stability, Structural Support and Fusion Potential

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      BOSTON M.A., Oct. 27, 2016 – Today DePuy Synthes Spine* announced the launch of the ZERO-P NATURAL™ Plate to help maintain stability and support bone growth in spinal fusion procedures in the neck. The ZERO-P NATURAL Plate is designed for use with the CC Natural spacer, an allograft spacer that offers structural support and fusion potential. The announcement was made in Boston at the North American Spine Society (NASS) annual meeting.

      The anterior plate and CC Natural allograft spacer are assembled together outside of the operating field, allowing for simultaneous insertion into the disc space during anterior cervical discectomy fusion (ACDF) procedures. The ZERO-P NATURAL Plate is anchored by four locking screws, which form a rigid bone wedge for stability.[i]

      Allograft interbody spacers are considered a primary choice for ACDF, representing 50 percent of all implanted cervical fusions.[ii] These spacers, including the CC Natural allograft spacer, work as a bridge to allow the natural bone to grow through the surface to support fusion.

      The ZERO-P NATURAL Plate is the newest addition to the DePuy Synthes zero-profile family of products, which do not protrude past the anterior wall of the vertebral body, limiting the risk of damage to vessels and adjacent soft tissue. These plates are designed to prevent contact with adjacent levels. Cervical plates placed near adjacent level discs may contribute to bone formation near or around the adjacent level.[iii]

      “Compared to ACDF with a traditional plate and allograft, there is no need to expose the vertebral bodies beyond their endplates, resect anterior osteophytes, or remodel the anterior surface of the vertebral bodies,” said Peyman Pakzaban, MD, FAANS, Houston MicroNeurosurgery.** “The insertion of a pre-fabricated allograft and the zero-profile plate is performed in one combined step.”

      Dan Wildman, Platform Leader, DePuy Synthes Spine added, “DePuy Synthes has a strong track record in providing solutions that help improve patient outcomes in cervical spine fusion, and the ZERO-P NATURAL Plate is the latest example of our focus on innovation that serves customers and patients while promoting surgical efficiency.”

      The CC Natural allograft spacer is processed by the Musculoskeletal Transplant Foundation, following stringent standards in tissue quality and safety through their approach to donor selection and allograft processing.

      About DePuy Synthes Companies

      DePuy Synthes Companies, Part of the Johnson & Johnson Family of Companies, provides one of the most comprehensive portfolios of orthopaedic solutions in the world. DePuy Synthes Companies solutions, in specialties including joint reconstruction, trauma, neurological, craniomaxillofacial, spinal surgery and sports medicine, are designed to advance patient care while delivering clinical and economic value to health care systems worldwide. For more information, visit


      ©DePuy Synthes 2016. All rights reserved.
      * A division of DePuy Orthopaedics, Inc.
      ** Consultant to DePuy Synthes Spine
      The third-party trademarks used herein are trademarks of their respective owners.

      DSUS/SPN/1016/1441a 10/16

      [i] Bench test results may not necessarily be indicative of clinical performance. The ZERO-P NATURAL Plate and an MTF CC Natural allograft spacer was compared to a one level VECTRA-ONE ™ Cervical Plate with an MTF CC Natural allograft spacer in a cyclic cadaveric range of motion study. The ZERO-P NATURAL Plate was also compared to a one level VECTRA-ONE Cervical Plate in mechanical testing per ASTM F1717. Test numbers 0000220895 and 0000252409.
      [ii] Millenium Research Group, US Markets for Spinal Implants 2013, Table 178: Cervical IBD Fusions, by Material, US
      [iii] Park, J.B., Y.S. Cho and K.D. Riew. 2005. “Development of adjacent-level ossification in patients with an anterior cervical plate.” J. Bone Joint Surg. Am. 87:558-563.

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