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Tuberculosis

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Johnson & Johnson Announces Series of Youth Initiatives Aimed at Helping to Empower a Generation to End Tuberculosis
Johnson & Johnson Announces Series of Youth Initiatives Aimed at Helping to Empower a Generation to End Tuberculosis
Jennefer Wetzel, Ganendra Awang Kristandya, Zolelwa Sifumba, M.D., and Saurabh Rane are working to end TB alt
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“We Want a World Without Tuberculosis in Our Lifetimes”
“We Want a World Without Tuberculosis in Our Lifetimes”
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Johnson & Johnson Announces Five Initiatives to Help Find the ‘Missing Millions’ of Undiagnosed People Living with Tuberculosis
Johnson & Johnson Announces Five Initiatives to Help Find the ‘Missing Millions’ of Undiagnosed People Living with Tuberculosis
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2 Pandemics, 1 Goal: Meet 4 Innovators with High-Tech Ideas for Fighting Tuberculosis in the Time of COVID-19
2 Pandemics, 1 Goal: Meet 4 Innovators with High-Tech Ideas for Fighting Tuberculosis in the Time of COVID-19
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J&J Commits $500MM Over Four Years to Combat HIV and TB
J&J Commits $500MM Over Four Years to Combat HIV and TB
Young adult male alt
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From Actor to Advocate: A New MTV Star Opens Up About the TB Epidemic
From Actor to Advocate: A New MTV Star Opens Up About the TB Epidemic
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The Quest to End Tuberculosis: 14 Memorable Moments in Innovation
The Quest to End Tuberculosis: 14 Memorable Moments in Innovation
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Ending Tuberculosis is Good Business
Ending Tuberculosis is Good Business

espite being preventable and curable, tuberculosis (TB) is among the world’s deadliest infectious diseases, killing 1.5 million people in 2020—more than HIV/AIDS and malaria combined. Underserved communities bear the largest burden, with more than 95% of TB-related deaths occurring in low- and middle-income countries, but this airborne disease knows no borders.

Growing drug resistance is compounding this public health challenge. In 2020, there were nearly half a million new cases of drug-resistant (DR-TB), which does not respond to the most frequently used first-line TB medicines. Just over 150,000 of these patients were diagnosed, meaning there are approximately 350,000 people with DR-TB who do not know they are infected. Drug-resistant TB now accounts for nearly one-third of all deaths directly attributable to antimicrobial resistance (AMR). Disruptions to health systems and diversion of resources caused by the COVID-19 pandemic are worsening the situation, resulting in 1.3 million fewer people diagnosed and reported for TB in 2020 than in 2019 and deaths increasing for the first time in a decade.

For nearly 20 years, both in the lab and at the last mile of healthcare in countries impacted by TB and DR-TB, Johnson & Johnson has been supporting global efforts to end TB and combat AMR.

Our Mission: Enabling a World Without TB
Our Mission: Enabling a World Without TB
In 2012, our medicine for pulmonary MDR-TB was granted accelerated approval by the United States Food and Drug Administration (U.S. FDA) for use as part of a combination therapy in adults when an effective treatment regimen cannot otherwise be provided. This was the first targeted TB drug with a novel mechanism of action to be approved in more than 40 years.

Today, our TB medicine is approved in many countries around the world, including in many high-burden countries, and registration efforts are ongoing in several others. It is also available to more than 130 low- and middle-income countries procuring the medicine through the Stop TB Partnership’s Global Drug Facility.

By the Numbers

Courses of our medicine delivered to date
Courses of our medicine provided for free through a four-year donation program
TB by the Numbers: 105,000 courses of our medicine provided for free through a four-year donation program alt
Countries accessing our medicine, including the 30 highest-burden countries
Countries in which our medicine has been approved
TB by the Numbers: 69 countries in which our medicine has been approved alt

Our 10-Year Initiative

In September 2018, Johnson & Johnson reaffirmed its continued commitment to the fight against TB by announcing a new 10-year initiative with three pillars:

  • Expanding access to treatment by offering a not-for-profit price to 130+ low- and middle-income countries, as well as non-governmental organizations, procuring our medicine through the Stop TB Partnership’s Global Drug Facility
  • Supporting global efforts to help find the “missing millions” of people with undiagnosed TB and MDR-TB and connect them to care, including by training health workers, ensuring careful stewardship of our MDR-TB medicine to protect its long-term effectiveness, engaging youth and raising community awareness

Our Global Efforts to End TB

Champions to #EndTB

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TB is an often-overlooked area in global health, and our 10-Year Initiative aims to change that. We’re working and partnering in new and unprecedented ways to modernize treatment, improve patient-finding and connect more patients with care – all with the goal of ending TB once and for all.

— Martin Fitchet, Global Head, Global Public Health, Johnson & Johnson
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To build a world without TB, we must bring this disease out of the shadows and address the biggest barriers that prevent people from seeking care. Young people can play a key role in bringing about this change, which is why it’s so important to meaningfully invest in the potential of youth as champions of change for themselves, their families, their peers and their communities.

— Anna Caravaggio, Vice President, Global Public Health Franchises, Johnson & Johnson
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The greatest opportunity to accelerate the fight against TB is right now in this new decade.

— Ana-Maria Ionescu, Global Marketing Leader, Tuberculosis, Global Public Health
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What inspires me to fight TB is our mothers, our fathers, our patients, our nurses, our healthcare providers.

— Erwin Benedicto, Head of Medical Affairs, Johnson & Johnson Philippines
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We can’t beat TB alone. That’s why we’re honored to join forces with our partners in the quest to create the first pan-TB treatment. Together, we can transform TB treatment and end this disease once and for all.

— Ruxandra Draghia-akli, M.D., Ph.D., Global Head, Global Public Health R&D
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Johnson & Johnson is advancing the fight against TB by doing much beyond the pill. We are engaging with partners at the national and international levels to ensure that we work with them to build the capacity and the systems needed to ensure that treatment is accessible.

— Vandita Gupta, Franchise Head, Infectious Diseases and Vaccines, Janssen India
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I'm committed to tackling TB because TB is a neglected disease. A lot of other diseases have gotten a lot of public focus ... I'm really committed to making it history. And we can. It's a curable disease.

— Koné Kaniga, Director, Project Scientist, TB, Janssen R&D
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When we end TB, patients and families can go back to their normal lives. Then, we can apply and scale up learnings from TB elimination efforts to help more patients in other areas.

— Salinee Vongpanich, Regional Public Health Access Lead, Johnson & Johnson Southeast Asia
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News and Updates

Innovation
March 24, 2022
“We Want a World Without Tuberculosis in Our Lifetimes”
Our Company
March 24, 2022
Johnson & Johnson Announces Series of Youth Initiatives Aimed at Helping to Empower a Generation to End Tuberculosis
Our Company
November 18, 2021
Johnson & Johnson is Proud to Lead Efforts to Outpace Antimicrobial Resistance
Our Company
July 09, 2021
Johnson & Johnson Launches Network of Global Health Discovery Centers that Aim to Speed Up Science and Tackle Pandemic Threats
Innovation
March 24, 2021
Building Resilient Health Systems Through Further Investments in TB
Our Company
March 24, 2021
Johnson & Johnson Announces Five Initiatives to Help Find the ‘Missing Millions’ of Undiagnosed People Living with Tuberculosis
Innovation
March 24, 2021
2 Pandemics, 1 Goal: Meet 4 Innovators with High-Tech Ideas for Fighting Tuberculosis in the Time of COVID-19
Innovation
March 24, 2021
As 2030 Deadline Looms We Must Accelerate Progress Against TB
Innovation
March 23, 2021
Advancing the Future of Tuberculosis (TB) Treatment
Innovation
December 10, 2020
3 Ways Johnson & Johnson Is Innovating to Help Fight Tuberculosis
Our Company
July 09, 2020
Statement attributed to Paul Stoffels on the occasion of the launch of the AMR Action Fund
Innovation
July 06, 2020
Stop TB Partnership and Johnson & Johnson, with support from USAID and The Global Fund, Announce Price Reduction for SIRTURO® (bedaquiline) for Treatment of Drug-Resistant Tuberculosis in Low- and Middle-Income Countries
Innovation
May 27, 2020
U.S. FDA Approves New Pediatric Formulation of SIRTURO® (bedaquiline) as Part of Combination Therapy to Treat Children with Pulmonary Multidrug-Resistant Tuberculosis
Innovation
May 27, 2020
J&J Launches Quickfire Challenge to Support Continuity of Care for DR-TB Patients During COVID-19
Our Company
March 24, 2020
Statement on the Occasion of World Tuberculosis Day
Innovation
February 27, 2020
First-of-Its-Kind Global Collaboration Launched to Develop Transformative Treatment Regimens for Tuberculosis
Our Company
January 23, 2020
Johnson & Johnson Recognized as Industry Leader in New AMR Benchmark
Our Company
January 22, 2020
Ending Tuberculosis is Good for Business: New Initiative Launched to Catalyze Action to End TB in the Workplace
Innovation
January 16, 2020
Johnson & Johnson Collaborates with The MTV Staying Alive Foundation to Launch Youth-Focused “Edutainment” Campaign Focused on Tuberculosis & Other Health Issues in India
Innovation
December 16, 2019
World Health Organization Recommends the Use of Bedaquiline-Containing Treatment Regimens For All Drug-Resistant Tuberculosis Patients
Our Company
October 30, 2019
Johnson & Johnson Expands Efforts to Help End Tuberculosis in India
Our Company
October 04, 2019
Johnson & Johnson Commits $500 Million Investment Over Four Years to Help End the Epidemics of HIV and Tuberculosis
Global Public Health
August 14, 2019
Statement on U.S. FDA Approval of Pretomanid as Part of Bedaquiline-Containing “BPaL” Regimen
Innovation
August 09, 2019
Janssen Announces U.S. FDA Accelerated Approval for SIRTURO® (bedaquiline) as Part of Combination Therapy to Treat Adolescents with Pulmonary Multidrug-Resistant Tuberculosis
Innovation
July 23, 2019
Johnson & Johnson Establishes International Consortium to Advance Pioneering Science in the Fight to End Tuberculosis
Our Company
June 26, 2019
FACT SHEET: Safeguarding Bedaquiline for Drug-Resistant Tuberculosis (DR-TB) Treatment
Innovation
May 07, 2019
The Cost of Complacency: Economist Intelligence Unit Report Underscores Major Gaps in World’s Response to Drug-Resistant Tuberculosis
Our Company
May 07, 2019
INFOGRAPHIC: DR-TB—The Time to Act is Now
Our Company
February 13, 2019
Statement on Johnson & Johnson’s Commitment to TB in India
Innovation
September 24, 2018
Johnson & Johnson Announces 10-year Initiative to Help End Tuberculosis, the World’s #1 Infectious Killer
Read More News

Learn Why Now’s the Time to Act

Pathway to Progress

J&J Announces New Youth-Focused Initiatives

Johnson & Johnson announces a series of initiatives aimed at helping empower a generation of youth to end TB in support of the Company’s efforts to help find the “missing millions.”

New Compound Is Identified

Janssen investigates possible compound for the treatment of MDR-TB.

Janssen’s MDR-TB Medicine Shows Promise

Janssen team publishes study in Science showing new drug killed TB bacteria—including drug-resistant bacteria—in the test tube and in a mouse model at faster rate than existing TB drugs.

Medicine Receives Accelerated FDA Approval

Our MDR-TB medicine is granted accelerated approval by the U.S. FDA as the first targeted drug with a novel mechanism of action against TB in more than 40 years.

J&J enters agreement for Russia and CIS alt

Agreement Signed for Russia and CIS

Our company enters into a commercial licensing agreement with JSC Pharmstandard for the registration, commercialization and manufacturing of MDR-TB medicine for Russia and several other countries in the region.

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Europe Grants Conditional Approval

Following a positive opinion from the European Medicines Agency, the European Commission grants conditional approval of our medicine for MDR-TB.

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Johnson & Johnson Enters Collaboration With Global Drug Facility

This partnership with a procurement agent for the Stop TB Partnership’s Global Drug Facility (GDF) helps to facilitate access to the company’s MDR-TB medicine.

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Collaboration Announced to Further Evaluate Medicine

Janssen announces collaboration with the International Union Against TB and Lung Disease (The Union) to include our MDR-TB medicine in two arms of the STREAM study, an ongoing trial to evaluate MDR-TB treatment regimens.

Bedaquiline Donation Program alt

Johnson & Johnson Launches Four-Year Donation Program

Our company commits to provide up to 30,000 courses of our medicine, free of charge, in up to 110 eligible countries through a donation program with USAID and Pharmstandard (quantities later increased, see March 2019).

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MDR-TB Medicine Added to WHO Essential Medicines List

The World Health Organization adds our MDR-TB medicine to its Essential Medicines List.

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Janssen Wins Prestigious International Award

Our MDR-TB medicine receives an International Prix Galien Award, recognizing excellence in scientific innovation to improve human health.

Johnson & Johnson Announces Extension of Donation Program

In response to high demand, Johnson & Johnson commits to provide an additional 30,000 courses of treatment through its donation program with USAID and JSC Pharmstandard; ultimately donated 105,000 courses (see March 2019).

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South African Government Leads the Way

South Africa becomes the first country to recommend a bedaquiline-containing, injection-free regimen for all eligible MDR-TB patients.

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Johnson & Johnson Offers Not-for-Profit Price to Eligible Countries

Johnson & Johnson announced that our MDR-TB medicine would be made available at a not-for-profit price to more than 130 countries procuring our medicine through the Stop TB Partnership’s Global Drug Facility.

New Study Suggests Cost-Effectiveness of Our MDR-TB Medicine

A new cost-effectiveness study suggests both long- and short-course regimens containing our MDR-TB drug, without injectables, are cost-effective and provide significant health system savings.

Johnson & Johnson Announces 10-Year TB Initiative

Johnson & Johnson announces new 10-year TB initiative aimed at improving case finding, expanding treatment access and advancing R&D.

WHO Finalizes New MDR-TB Treatment Guidelines

The World Health Organization announces revised treatment guidelines for MDR-TB that categorize our medicine as a “Group A” medicine to be prioritized when constructing a conventional (long-course) regimen for MDR-TB.

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Conclusion of Successful Donation Program

Johnson & Johnson ultimately committed 105,000 courses of our MDR-TB medicine, free of charge, to 80 countries through four-year donation program with USAID and JSC Pharmstandard.

Man in India alt

Johnson & Johnson-Supported EIU Report Launches

Report estimates DR-TB deaths in a single year cost the global economy at least US$17.8 billion and calls for action to end the epidemic.

Johnson & Johnson Launches New R&D Collaboration

Johnson & Johnson partners with the EU’s Innovative Medicines Initiative and eight European academic and research institutions to launch a new collaborative aimed at accelerating the discovery of new TB medicines.

J&J commits $500 million to help end HIV and TB

J&J announces four-year commitment, focused on developing new innovations and accelerating the delivery of existing and new tools to combat both epidemics.

FDA Approves Our MDR-TB Medicine for Adolescents

The U.S. FDA grants approval for the medicine as part of combination therapy for eligible patients over the age of 12 and younger than 18 with pulmonary multidrug-resistant tuberculosis (MDR-TB).

WHO Recommends All-Oral DR-TB Treatment Regimens

The World Health Organization (WHO) recommends the use of all-oral regimens containing our medicine for all drug-resistant tuberculosis patients.

New Global Collaboration to Develop Transformative Treatments

Johnson & Jonson joins a global consortium of philanthropic, non-profit and private sector organizations to accelerate the development of novel “pan-TB” treatment regimens.

FDA Approves Pediatric Formulation of Our MDR-TB Medicine

Johnson & Johnson receives the first regulatory approval for the pediatric formulation of our medicine.

J&J and Partners Announce Efforts to Scale-Up Access

J&J and Stop TB Partnership announce joint efforts to accelerate scale-up of WHO-recommended, all-oral treatment regimens and drive progress toward the global goal of ending TB.

J&J Announces Initiatives to Find the “Missing Millions”

Johnson & Johnson announces five initiatives to help find and deliver care to the “missing millions” of adults and children living with TB who have not yet been diagnosed.

Pediatric Formulation of MDR-TB Medicine Receives European Commission Approval

J&J’s pediatric TB formulation is approved for use by the European Commission.

J&J Launches Centers for Global Health Discovery

First Satellite Center for Global Health Discovery is launched at the London School of Hygiene & Tropical Medicine, aimed at accelerating new TB drug regimens.

Pediatric Formulation of MDR-TB Medicine Added to WHO Essential Medicines List

WHO adds the pediatric-friendly formulation of our MDR-TB medicine to the Model List of Essential Medicines (EML) and EML for children.

March, 2022

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January 2013

J&J enters agreement for Russia and CIS

March 2014

European Medicines Agency

April 2014

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November 2014

Scientists with microscope

April and December 2015

Bedaquiline Donation Program

May 2015

Medicine

December 2016

Prix Galien

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Man in South Africa

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Man in India

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