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HomeMedia CenterPress releases Medical technologiesDePuy Synthes Introduces the INHANCE™ Shoulder System, a First-to-Market, Fully Integrated Shoulder Arthroplasty System

DePuy Synthes Introduces the INHANCE™ Shoulder System, a First-to-Market, Fully Integrated Shoulder Arthroplasty System

The INHANCE™ Shoulder System empowers surgeons to treat a broad range of cases with a streamlined, comprehensive implant offering that features common instrumentation and unique interoperative flexibility

Designed for hospitals as well as outpatient and ASC settings where economic value and operational efficiency are critical considerations

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RAYNHAM, MA – August 18, 2021 – Today, The Johnson & Johnson Medical Devices Companies* announced that DePuy Synthes, The Orthopaedics Company of Johnson & Johnson,** introduces the INHANCE™ Shoulder System, a first-to-market, fully integrated shoulder arthroplasty system. The system is designed with an intuitive stemless-first surgical approach that aligns with how surgeons approach patient care. The INHANCE Shoulder System is the first shoulder system to offer surgeons the ability to seamlessly transition from stemless to stemmed implants during surgical procedures.

There are many reasons surgeons may need to transition to a different surgical treatment option during shoulder arthroplasty procedures, including humeral bone quality and severity of glenoid bone loss, or the extent of rotator cuff deficiency. The INHANCE Shoulder System empowers surgeons to treat a broad range of cases by providing an intelligently-designed implant offering that is both streamlined and comprehensive, and also features unique interoperative flexibility, addressing a critical unmet clinical need. The common instrumentation of the INHANCE Shoulder System also facilitates greater OR efficiency[1].

This new class of shoulder system also features:

  • Reusable instrumentation optimized for efficiency with only two instrument cases for stemless and stemmed anatomic procedures
  • A comprehensive size range of anatomic stemless and stemmed inlay humeral implants that share a common geometrical shape to easily fixate to the humerus
  • A unique circular anatomic glenoid component compatible with any sized humeral head, and the ONE STEP PREP™ Glenoid Reamer that reduces the number of surgical steps, eliminating the need to separately ream the backside of the implant, drill the central hole, and drill the peripheral holes[2]

“Advancements in shoulder arthroplasty have enabled a broader range of surgical treatment over the past decade but have increased the complexity and cost of preparing for each surgical case,” said J. Michael Wiater, MD, Vice Chairman, Chief of Shoulder Surgery and Professor of Orthopedic Surgery, Oakland University William Beaumont School of Medicine***. “The INHANCE Shoulder System can empower surgeons to seamlessly alter their surgical flow, while simultaneously keeping their focus on the patient, and has the potential to reduce OR time.”

The INHANCE Shoulder System is also designed for the shift in site of care of certain orthopedic procedures towards outpatient and ambulatory surgery centers where economic value and operational efficiency are critical considerations. The INHANCE Shoulder System’s implants are designed to preserve bone, provide immediate and long-term fixation, and facilitate intra-operative flexibility while simplifying preparation for various surgical treatment options3,4.

Additional features of the system include:

  • Novel implant designs that are additively manufactured via state-of-the-art 3D laser printing incorporating the UNITI™ Porous Structure, which was created specifically for biological fixation in the shoulder.[3i]
  • Only two reusable instrument cases are required, reducing the number of trays needed to be reprocessed, stored, and retrieved
  • Advanced cross-linked Vitamin E polyethylene for desired wear characteristics and oxidative stability, which becomes an important consideration to reduce the risk of revision and complications[4], which can potentially reduce the economic burden to the healthcare system.

DePuy Synthes acquired the INHANCE Shoulder System through a multi-year, strategic agreement with Ignite Orthopedics, LLC. Through this collaboration, DePuy Synthes will launch the core system plus additional product innovations. The INHANCE Shoulder System was designed in collaboration with a team of leading shoulder arthroplasty surgeons and is competitively positioned to address the increasing complexity of shoulder replacement procedures by integrating less invasive clinical options aligned with how surgeons approach patient care.

“At DePuy Synthes we’re focused on delivering innovations to address the most pressing needs of surgeons today while anticipating market dynamics that drive clinical trends and the needs of tomorrow,” said Russell Powers, Worldwide President, Sports Medicine and Shoulder Reconstruction, DePuy Synthes****. “The INHANCE Shoulder System reflects our strong commitment to lead in shoulder arthroplasty by taking innovation to the next level.”

About Johnson & Johnson Medical Devices Companies
At Johnson & Johnson Medical Devices Companies, we are helping people live their best lives. Building on more than a century of expertise, we tackle pressing healthcare challenges, and take bold steps that lead to new standards of care while improving people’s healthcare experiences. In surgery, orthopaedics, vision and interventional solutions, we are helping to save lives and paving the way to a healthier future for everyone, everywhere.

About DePuy Synthes
DePuy Synthes, the Orthopaedics Company of Johnson & Johnson, provides one of the most comprehensive orthopaedics portfolios in the world that helps heal and restore movement for the millions of patients we serve. DePuy Synthes solutions, in specialties including joint reconstruction, trauma, extremities, craniomaxillofacial, spinal surgery and sports medicine, in addition to the VELYS™ Digital Surgery portfolio, are designed to advance patient care while delivering clinical and economic value to health care systems worldwide.

Building on our proud product innovation and legacy of industry firsts, we are reimagining the orthopaedic landscape with new advancements in medical technologies and digital surgery across the entire continuum of care to Keep People Moving today and tomorrow. For more information, visit

* Comprising the surgery, orthopaedics, vision and interventional solutions businesses within Johnson & Johnson’s Medical Devices segment.
** DePuy Synthes represents the products and services of DePuy Synthes, Inc. and its affiliates.
*** Dr. Wiater is a design surgeon who developed the INHANCE Shoulder System and is a paid consultant for DePuy Synthes.
**** Russell Powers is an employee of Medical Device Business Services, Inc.

Cautions Concerning Forward-Looking Statements
This press release contains “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995 regarding the INHANCE Shoulder System. The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections of DePuy Synthes, Inc. and/or Johnson & Johnson. Risks and uncertainties include, but are not limited to uncertainty of commercial success; challenges to patents; competition, including technological advances, new products and patents attained by competitors; manufacturing difficulties and delays; product efficacy or safety concerns resulting in product recalls or regulatory action; changes to applicable laws and regulations, including global health care reforms; changes in behavior and spending patterns of purchasers of health care products and services; and trends toward health care cost containment. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson’s Annual Report on Form 10-K for the fiscal year ended January 3, 2021, including in the sections captioned “Cautionary Note Regarding Forward-Looking Statements” and “Item 1A. Risk Factors,” and in the company’s most recently filed Quarterly Report on Form 10-Q, and the company’s subsequent filings with the Securities and Exchange Commission. Copies of these filings are available online at, or on request from Johnson & Johnson. Neither the Johnson & Johnson Medical Devices Companies nor Johnson & Johnson undertakes to update any forward-looking statement as a result of new information or future events or developments.

184907-210802 DSUS
© DePuy Synthes 2021. All rights reserved.
Please refer to the instructions for use for a complete list of indications, contraindications, warnings and precautions.


[1] INHANCE Surgical Step Comparison (Glenoid and Humeral) DPS - 103814569 Rev 1 and DPS – 103814569. See document summary tab.
[2] INHANCE Surgical Step Comparison DPS 103814569 Rev 1 -. See document summary tab.
[3] Ignite TR-200803 REV 00 - X1 Fine 3D Printed Porous Eval Including Appendix’s’ A thru E
[4] Ignite Characterization of AO-HXLPE Report

Media Contact:
Erin Walsh

Investor Contact:
Sarah Wood

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