- EMEA Innovative Medicine
- Our innovation
- Focus areas
- Oncology
- B-cell malignancies
B-cell malignancies

Our precise focus in B-cell malignancies
B-cell malignancies can broadly be categorised into Hodgkin and non-Hodgkin lymphomas.[4] There are many different types, each with distinct characteristics, behaviours and treatment approaches, and each person’s experience with the disease is unique. While much progress has been made over the past decade, we remain focused on continuing to develop new treatment options with reduced side effects that can improve quality of life and prolong the duration of remission for all patients with these complex blood cancers. We are pioneering therapeutic advances to intercept haematologic malignancies and one day, deliver cures.

Our approach to research
However, unmet medical needs remain for these diverse forms of blood cancer.[8] We have made it our mission to change the trajectory of these diseases and bring life-changing therapies to patients and their families. With over three decades of industry leadership in haematologic malignancies, we continue to advance the next wave of innovations so that we can get in front of cancer.
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[1] National Library of Medicine. B Cell Metabolism and Autophagy in Autoimmunity - PMC (nih.gov). Available at:
https://pmc.ncbi.nlm.nih.gov/articles/PMC8215381/
[2] National Cancer Institute. Understanding Cancer. Available at:
https://www.cancer.gov/about-cancer/understanding
[3] National Library of Medicine. Diffuse Large B-Cell Lymphoma - PMC (nih.gov).
https://www.ncbi.nlm.nih.gov/books/NBK557796/
[4] National Cancer Institute. Lymphoma-patient version. Available at:
https://www.cancer.gov/types/lymphoma
[5] Yosifov DY. From biology to therapy: the CLL success story. Hemasphere. 2019;3: e175. Accessed February 2025.
[6] Schieber M. Current overview and treatment of mantle cell lymphoma. F1000Res. 2018;7: F1000 Faculty Rev-1136. doi:10.12688/f1000research.14122.1 Accessed February 2025.
[7] Pooja A. Updates in prognostication and treatment of Waldenström’s macroglobulinemia, Hematology/Oncology and Stem Cell Therapy. 2019; 12:4: 179-188. doi.org/10.1016/j.hemonc.2019.05.002. Accessed February 2025.
[8] Cheson B D. Diffuse large B-cell lymphoma: new targets and novel therapies. Blood Cancer Journal. 2021;11,68. Accessed February 2025.
CP-506089
February 2025